Nusinersen
Availability of ACE Drug Guidance
Yes
Biologics Drug Information Overview
No
Subsidy Information and Financing Scheme
No
Active ingredient: Nusinersen
General information
Subsidy Information and Financing Scheme
Not Applicable
Drug Guidance for Subsidy
01/07/2026 Nusinersen and risdiplam for treating spinal muscular atrophy (opens in new tab)
The Ministry of Health’s Drug Advisory Committee has recommended:
Risdiplam 0.75 mg/mL powder for oral solution and 5 mg tablet for treating:
Symptomatic Type 1, 2 or 3 spinal muscular atrophy (SMA) in patients who are/were 18 years of age or under at the time of initial treatment with risdiplam or nusinersen;
Symptomatic Type 1, 2 or 3 SMA in patients aged 19 years or above who had not initiated treatment with risdiplam or nusinersen prior to 19 years of age despite onset of signs/symptoms of SMA;
Pre-symptomatic SMA in patients who are/were under 3 years of age at the time of initial treatment with risdiplam or nusinersen; and
SMA in patients who have experienced a regression in a developmental state despite treatment with gene therapy.
Funding status
[R] Risdiplam 0.75 mg/mL powder for oral solution and 5 mg tablet are recommended for inclusion on the Medication Assistance Fund (MAF) for the abovementioned indications from 1 August 2024 and 1 September 2026, respectively.
[R] Risdiplam should be used in line with the additional clinical criteria listed in the Annex.
[NR] MAF assistance does not apply to nusinersen for treating SMA.
Registered Product(s) Information
Clinical and product info
Clinical info | Product Info |
|---|---|
Information under the Indication, Dosage and Contraindication sections are extracted from the relevant Package Insert/Patient Information Leaflet of the product available on HSA Infosearch. For more information, please refer to the product's Package Insert/ Patient Information Leaflet available on HSA Infosearch (opens in new tab). The information provided is for informational purposes only, and is not exhaustive. The information provided is not a substitute for professional medical advice. Please consult a qualified healthcare provider for any medical advice. | Information available here are product details as registered with the HSA. As this website is updated monthly, please refer to HSA Infosearch (opens in new tab) for the most updated product information. |
Intrathecal
* Clinical information is available for this product.