PMS-CHOLESTYRAMINE POWDER [SIN07426P]
Active ingredients: PMS-CHOLESTYRAMINE POWDER
Product Info
PMS-CHOLESTYRAMINE POWDER
[SIN07426P]
Product information
Active Ingredient and Strength | CHOLESTYRAMINE RESIN - 4 G |
Dosage Form | POWDER |
Manufacturer and Country | PHARMALAB INC - CANADA |
Registration Number | SIN07426P |
Licence Holder | SYNMOSA BIOPHARMA PTE. LTD. |
Forensic Classification | PRESCRIPTION ONLY MEDICINES |
Anatomical Therapeutic Chemical (ATC) code | C10AC01 |
Prescription-only Medicines with Exemptions for Supply without Prescription | NA |
Indication
INDICATIONS
Cholestyramine resin is indicated as an adjunct to dietary therapy and exercise to decrease elevated serum cholesterol in the management of primary type IIa and type IIb hypercholesterolemia (elevated low density lipoprotein) and to reduce the risks of antherosclerotic coronary artery disease and myocardial infarction. Although cholestyramine may also lower plasma cholesterol concentration in patients with other types of hyperlipoproteinemia, the drug may increase plasma triglyceride concentrations and, therefore, should not be used alone in patients with hyperlipidemias associated with hypertriglyceridemia.
Cholestyramine resin is indicated as a symptomatic control of diarrhea caused by increased bile acids due to short bowel syndrome.
Cholestyramine resin is indicated for the relief of pruritus associated with partial biliary obstruction.
Dosing
DOSAGE AND ADMINISTRATION
Cholestyramine resin is administered orally. To avoid oesophageal irritation or blockage or intestinal blockage, the drug should not be taken in its dry form. pms-Cholestyramine Powder should always be mixed with an appropriate fluid prior to ingestion (see Preparation – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information).
To minimize gastrointestinal side effects and to familiarize the patient with pms-Cholestyramine, therapy should be initiated with one dose of pms-Chotestyramine Powder daily. After one to two days the dosage can be increased to meet the patient's needs.
The usual initial adult dosage of cholestyramine resin is 4 grams one to six times daily. Subsequent dosage should be adjusted according to the patient's requirements and response.
A pediatric dosage schedule has not been established.
Contraindications
CONTRAINDICATIONS
Cholestyramine resin is contraindicated in patients with complete biliary obstruction in which no bile products reach the intestine.
It is also contraindicated in patients who are hypersensitive to the drug or to any ingredient in its formulation.
Pms-Cholestyramine resin should not be taken in its dry form. Cholestyramine may delay or reduce absorption of other medications administered concurrently because of its anion-binding activity; administration of other medications 1 hour before or 4 to 6 hours after cholestyramine is recommended, although absorption of some medications is impaired even then.
