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National Drug Formulary

C-FLOX 500 TABLETS 500 MG [SIN11303P]

Active ingredients: C-FLOX 500 TABLETS 500 MG

View product's general information
Last updated 24 April 2026

Product Info

C-FLOX 500 TABLETS 500 MG

[SIN11303P]

Product information

Active Ingredient and Strength

CIPROFLOXACIN HCL EQV CIPROFLOXACIN - 555 MG

Dosage Form

TABLET, FILM COATED

Manufacturer and Country

INTAS PHARMACEUTICALS LTD - INDIA

Registration Number

SIN11303P

Licence Holder

APOTHECA MARKETING PTE LTD

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

J01MA02

Prescription-only Medicines with Exemptions for Supply without Prescription

NA

Indication

Indications:
C-Flox is indicated for the treatment of the following infections due to sensitive bacteria:

  1. Respiratory infections: Lobar and bronchopneumonia, acute and chronic bronchitis, acute exacerbation of cystic fibrosis, bronchiectasis, empyema.

  2. Ear, nose and throat infection: Otitis media, sinusitis, mastoiditis, especially infections due to Gram-negative bacteria.

  3. Intra-abdominal and biliary tract infections: Infective diarrhoea, typhoid fever, cholangitis, cholecystitis.

  4. Pelvic infections: Salpingitis, endometritis, pelvic inflammatory disease.

  5. Urinary tract infections: Uncomplicated and complicated urethritis, cystitis, pyelonephritis, prostatitis, epididymitis.

  6. Gonorrhoea: urethral, rectal and pharyngeal

  7. Bone and joint infections: Osteomyelitis, septic.

  8. Skin and soft tissue infections: Infected ulcers, wounds, abscesses, cellulitis, erysipelas, infected burns.

  9. Systemic infections: Septicemia, peritonitis.

Dosing

Dosage and Administration:
In adults, depending upon the type and severity of infection, C-Flox is given in a dose range of 250 mg–750 mg, administered twice daily for the period of 5–10 days.

Dosage and Administration in special situations:
In gonorrhoea, single dose of 250 mg (C-Flox-250) is given. In elderly patients no dosage adjustment is usually required. In patients with severe renal impairment (serum creatinine <20ml/minute), the usual dose may be reduced to half.

Contraindications

Under Contraindications, Warnings, Precautions:
A history of hypersensitivity to any of the quinolones is a contraindication to the use of C-Flox. C-Flox may cause CNS stimulation which may lead to tremor, restlessness or even seizures. So C-Flox should be used with caution in patients of epilepsy. Anaphylactic reactions have also been reported to the first dose of C-Flox.
The dose of C-Flox should be approximately adjusted in patients with impaired renal function. When prolonged therapy is given, the renal, hepatic and hemopoietic function must be periodically assessed.