OLICLINOMEL N4-550 E EMULSION FOR INFUSION [SIN12542P]

View product's general information

Last updated 28 July 2026

Product Info

OLICLINOMEL N4-550 E EMULSION FOR INFUSION

[SIN12542P]

Product information

Active Ingredient and Strength	CALCIUM CHLORIDE 2H₂O (IN COMPARTMENT 3) - 0.3 G/L GLUCOSE (AS GLUCOSE MONOHYDRATE) (IN COMPARTMENT 3) - 88 G/L GLYCINE (IN COMPARTMENT 2) - 2.27 G/L L-ALANINE (IN COMPARTMENT 2) - 4.56 G/L L-ARGININE (IN COMPARTMENT 2) - 2.53 G/L L-HISTIDINE (IN COMPARTMENT 2) - 1.06 G/L L-ISOLEUCINE (IN COMPARTMENT 2) - 1.32 G/L L-LEUCINE (IN COMPARTMENT 2) - 1.61 G/L L-LYSINE (AS HCL) (IN COMPARTMENT 2) - 1.6 G/L L-METHIONINE (IN COMPARTMENT 2) - 0.88 G/L L-PHENYLALANINE (IN COMPARTMENT 2) - 1.23 G/L L-PROLINE (IN COMPARTMENT 2) - 1.5 G/L L-SERINE (IN COMPARTMENT 2) - 1.1 G/L L-THREONINE (IN COMPARTMENT 2) - 0.92 G/L L-TRYPTOPHAN (IN COMPARTMENT 2) - 0.4 G/L L-TYROSINE (IN COMPARTMENT 2) - 0.09 G/L L-VALINE (IN COMPARTMENT 2) - 1.28 G/L MAGNESIUM CHLORIDE 6H₂O - 0.45 G/L POTASSIUM CHLORIDE - 1.19 G/L REFINED SOYA BEAN OIL + REFINED OLIVE OIL (IN COMPARTMENT 1) - 20 G/L SODIUM ACETATE 3H₂O\| SODIUM GLYCEROPHOSPHATE 5H₂O - 0.98 G/L
Dosage Form	EMULSION
Manufacturer and Country	BAXTER SA - BELGIUM AJINOMOTO NORTH AMERICA INCORPORATED (INTERMEDIATE) - UNITED STATES
Registration Number	SIN12542P
Licence Holder	BAXTER HEALTHCARE (ASIA) PTE LTD
Forensic Classification	GENERAL SALE LIST
Anatomical Therapeutic Chemical (ATC) code	B05BA10
Prescription-only Medicines with Exemptions for Supply without Prescription	NA

Indication

4.1 Therapeutic indications
Parenteral nutrition for adults and children greater than two years of age, when oral or enteral nutrition is impossible, insufficient or contraindicated.

Dosing

4.2 Posology and method of administration

Posology
The dosage depends on the patient’s energy expenditure, clinical status, body weight and the ability to metabolize the constituents of OLICLINOMEL, as well as additional energy intake or proteins taken orally or enterally; therefore the bag size chosen accordingly.
The administration may be continued for as long as is required by the patient’s clinical conditions.

Maximum daily dose
The maximum daily dose should not be exceeded in adult and paediatric patients. Due to the static composition of the multi-chamber bag, the ability to simultaneously meet all nutrient needs of the patient may not be possible. Clinical situations may exist where patients require amounts of nutrients varying from the composition of the static bag.

In adults
Requirements:
Average nitrogen requirements are 0.16 to 0.35 g/kg/day (approximately 1 to 2 g of amino acids/kg/day).
Energy requirements vary depending on the patient’s nutritional status and level of catabolism. On average these are 20 to 40 kcal/kg/day.

Maximum daily dose
The maximum daily dose is 40 ml/kg body weight (equivalent to 0.88 g of amino acids, 3.2 g of glucose and 0.8 g of lipids, 0.84 mmol of sodium and 0.64 mmol of potassium per kg), i.e. 2800 ml of the emulsion for infusion for a patient weighing 70 kg.

In adolescent and children greater than two years of age
There have been no studies performed in the paediatric population.

Posology:
The dosage is based on fluid intake and daily nitrogen requirements.
These intakes should be adjusted to take account of the child’s hydration status.
Daily fluid, nitrogen, and energy requirements continuously decrease with age.
The guidelines for maximal recommended hourly rate of infusion and volume per day for paediatric patients are:

Maximum Daily Dose

Maximum Hourly Rate

Method and duration of administration

For single use only.

It is recommended that after opening the bag, the contents should be used immediately, and not stored for subsequent infusion.

Appearance after reconstitution: homogenous liquid with a milky appearance.

For instructions for preparation and handling of the emulsion for infusion, see section 6.6 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information.

BY INTRAVENOUS ADMINISTRATION THROUGH A CENTRAL OR PERIPHERAL VEIN (due to the low osmolarity of OLICLINOMEL).

The recommended duration of the parenteral nutrition infusion is between 12 and 24 hours.

The administration flow rate must be adjusted taking into account the dose being administered, the daily volume intake, and the duration of the infusion (See Section 4.4 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information).

Normally, the flow rate should be increased gradually during the first hour.

Maximum infusion rate in adults:
As a general rule, do not exceed 3.0 ml/kg/hour of the emulsion for infusion, i.e. 0.06 g amino acids, 0.24 g glucose and 0.06 g lipids /kg body weight /hour.

As a general rule, do not exceed infusion rates of 0.10 g/kg/hour amino acids and/or 0.25 g/kg/hour glucose and/or 0.15 g/kg/hour lipids, except in particular cases.

Contraindications

4.3 Contraindications
The use of OLICLINOMEL N4-550E is contraindicated in the following situations:

In premature neonates, infants and children less than 2 years old, as the calorie‐nitrogen ratio and energy supply are inappropriate;
Hypersensitivity to egg, soya-bean, peanut proteins, or corn/corn products (see Section 4.4 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information), or to any other active substance or excipients listed in section 6.1 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information;
Congenital abnormalities of amino acid metabolism;
Severe hyperlipidaemia or severe disorders of lipid metabolism characterized by hypertriglyceridaemia;
Severe hyperglycaemia;
Pathologically elevated plasma concentrations of sodium, potassium, magnesium, calcium and/or phosphorus.

Government officials will never ask you to transfer money or disclose bank log-in details over a phone call.