Skip to main content
A Singapore Government Agency Website How to identify
Official website links end with .gov.sg
Secure websites use HTTPS
Look for a lock () or https:// as an added precaution. Share sensitive information only on official, secure websites.
Government officials will never ask you to transfer money or disclose bank log-in details over a phone call.

Call the 24/7 ScamShield Helpline at 1799 if you are unsure if something is a scam.

National Drug Formulary

PHENYLALPHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 50MCG/ML [SIN15668P]

Active ingredients: PHENYLEPHRINE HYDROCHLORIDE 60.9 MCG/ML EQV TO PHENYLEPHRINE

View product's general information
Last updated on 9 October 2026

Product Info

PHENYLALPHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 50MCG/ML

[SIN15668P]

Product information

Active Ingredient and Strength

PHENYLEPHRINE HYDROCHLORIDE 60.9 MCG/ML EQV TO PHENYLEPHRINE - 50 MCG/ML

Dosage Form

INJECTION, SOLUTION

Manufacturer and Country

LABORATOIRE AGUETTANT - FRANCE

Registration Number

SIN15668P

Licence Holder

INTEGA PTE LTD

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

C01CA06

Prescription-only Medicines with Exemptions for Supply without Prescription

NA

Indication

4.1 Therapeutic indications
Treatment of hypotension during general anaesthesia and locoregional anaesthesia, whether spinal or epidural, and whether for surgical or obstetric procedures.
Preventive treatment of hypotension during spinal anaesthesia for surgical or obstetric procedures.

Dosing

4.2 Posology and method of administration
Posology
Intravenous bolus injection:
Normal dose is 50 to 100 micrograms, which can be repeated until the desired effect is attained. The doses may be increased in the case of severe hypotension, but must not exceed a bolus of 100 micrograms.

Continuous infusion:
Initial dose is 25 to 50 micrograms/min. Doses can be increased up to 100 micrograms/min or reduced in order to maintain systolic blood pressure close to its reference value.
Doses between 25 and 100 micrograms/min have been considered effective in maintaining maternal blood pressure.

Renal impairment
Lower doses of phenylephrine may be needed in patients with impaired renal function.

Hepatic Impairment
Higher doses of phenylephrine may be needed in patients with cirrhosis of the liver.

Older people
Treatment of the elderly should be carried out with care.

Paediatric population
The safety and efficacy of phenylephrine in children have not been established. No data are available.

Method of administration:
Parenteral administration. Intravenous bolus injection or intravenous infusion. The pre-filled syringe is not suitable for use with a syringe pump.
PHENYLALPHA 50 micrograms/ml, solution for injection should only be administered by healthcare professionals with appropriate training and relevant experience.

Contraindications

4.3 Contraindications
Phenylephrine should not be used:

  • hypersensitivity to the active substance or to any of the excipients listed in section 6.1 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information;

  • in combination with non-selective monoamine oxidase inhibitors (MAOs) (or within 2 weeks of their withdrawal) due to risk of paroxysmal hypertension and possibly fatal hyperthermia (see section 4.5 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information);

  • in patients with severe hypertension or peripheral vascular disease due to the risk of ischemic gangrene or vascular thrombosis;

  • in patients with severe hyperthyroidism.