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National Drug Formulary

QUPRON TABLETS 250 MG [SIN09569P]

Active ingredients: QUPRON TABLETS 250 MG

View product's general information
Last updated 24 April 2026

Product Info

QUPRON TABLETS 250 MG

[SIN09569P]

Product information

Active Ingredient and Strength

CIPROFLOXACIN HCL EQV CIPROFLOXACIN - 250 MG

Dosage Form

TABLET, FILM COATED

Manufacturer and Country

SHIN POONG PHARMACEUTICAL CO LTD - KOREA, REPUBLIC OF

Registration Number

SIN09569P

Licence Holder

ZYFAS PHARMA PTE LTD

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

J01MA02

Prescription-only Medicines with Exemptions for Supply without Prescription

NA

Indication

【INDICATIONS】

  1. Susceptible organisms : E. coli, Shigella, Salmonella, Citrobacter, Klebsiella, Enterobacter, Serratia, hafnia, proteus (Indole positive & negative). Pseudomonas, Neisseria, Acinetobacter, Streptococcus, Chlamydia, Staphylococcus, Corynebacterium, Bacteroides, Clostridium

  2. Indications
    Respiratory infections, infections of oral cavity, teeth and jaw, infections of ear, nose and throat, infections of kidney or urinary passages, genital infections containing gonorrhea, gastrointestinal infections, infection and wound of soft tissue, infections of bone and joint, infections in gynecological and obstetric field, septicemia, cerebromeningitis, peritonitis, ophthalmologic infections and infections in bile secretory duct.

Dosing

【DOSAGE AND ADMINISTRATION】
1. Usually for adults, administer 250~500mg at meal intervals twice a day. In severe mixed infections, administer up to 750mg twice a day. In acute infections, usually treat for 5 to 10 days. After disappearance of symptoms, further administration is required at least for 3 days.

2. In patients with severe renal disorder, it should be administered according to the following dosage and administration.

Qupron Dosage Table 1



When only the concentration of serum creatinine clearance is known, the patient’s creatinine clearance can be estimated by using the following formulas:

Qupron Dosage Formula 1



In patient with severe cardiac failure and infections, 750mg can be administered once, but careful monitoring is required and the ciprofloxacin concentration should be periodically estimated. At that time, the peak serum concentration (obtained 1~2 hours after administration) should range from 2~4mcg/ml.

3. Dosage may be adjusted according to causative organisms and severity of symptom.

Contraindications

1. Contraindications
1) Patients previously found hypersensitive to it.
2) Pregnancy and nursing woman
3) Children and infants
4) Patients with hepatic disorder