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National Drug Formulary

FLORINEF TABLET 0.1 MG [SIN10680P]

Active ingredients: FLUDROCORTISONE ACETATE

View product's general information
Last updated on 9 October 2026

Product Info

FLORINEF TABLET 0.1 MG

[SIN10680P]

Product information

Active Ingredient and Strength

FLUDROCORTISONE ACETATE - 0.1 MG

Dosage Form

TABLET

Manufacturer and Country

HAUPT PHARMA AMAREG GMBH - GERMANY

Registration Number

SIN10680P

Licence Holder

DCH AURIGA SINGAPORE

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

H02AA02

Prescription-only Medicines with Exemptions for Supply without Prescription

NA

Indication

INDICATIONS AND USAGE

FLORINEF is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome.

Dosing

RECOMMENDED DOSAGE

Dosage depends on the severity of the disease and the response of the patient. The lowest possible dose should be used to control the condition being treated, and a reduction in dosage should be made (gradually) when possible.

Adrenocorticoid Insufficiency (chronic).

In Addison’s disease, the combination of FLORINEF with a glucocorticoid such as hydrocortisone or cortisone provides substitution therapy approximating normal adrenal activity.

The usual dose for adults, adolescents, and elderly patients is one tablet (0.1 mg) of FLORINEF daily – range: one tablet (0.1 mg) three times a week to two tablets (0.2 mg) daily. If treatment-associated hypertension develops, the dose should be reduced to 0.05 mg daily. FLORINEF is preferably administered in conjunction with cortisone (10 mg to 37.5 mg daily in divided doses) or hydrocortisone (10 mg to 30 mg daily in divided doses).

Salt-losing Adrenogenital Syndrome

The recommended dosage for treating salt-losing adrenogenital syndrome is one tablet (0.1 mg) to two tablets (0.2 mg) of FLORINEF daily.

Pediatric and Adolescent: One half tablet (0.05 mg) to one tablet (0.1 mg) daily.

Contraindications

CONTRAINDICATIONS

Corticosteroids are contraindicated in patients with systemic fungal infections and in those with suspected or known hypersensitivity to fludrocortisone or any of the inactive ingredients.