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National Drug Formulary

PANTOBEX DELAYED RELEASE TABLET 20MG [SIN16591P]

Active ingredients: PANTOPRAZOLE SODIUM SESQUIHYDRATE EQV PANTOPRAZOLE

View product's general information
Last updated on 9 October 2026

Product Info

PANTOBEX DELAYED RELEASE TABLET 20MG

[SIN16591P]

Product information

Active Ingredient and Strength

PANTOPRAZOLE SODIUM SESQUIHYDRATE EQV PANTOPRAZOLE - 20 MG

Dosage Form

TABLET, DELAYED RELEASE

Manufacturer and Country

BEXIMCO PHARMACEUTICALS LIMITED - BANGLADESH

Registration Number

SIN16591P

Licence Holder

GOLDPLUS UNIVERSAL PTE LTD

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

A02BC02

Prescription-only Medicines with Exemptions for Supply without Prescription

As an oral preparation containing not more than 20mg

  • Indication: For the relief of heartburn symptoms associated with acid reflux

  • Maximum daily dose: 20mg

  • Maximum supply: 14 days

  • Minimum age: 18 years

Indication

4.1. Therapeutic indications
Pantobex Delayed Release Tablet 20 mg

  • Mild reflux disease and associated symptoms (e.g. heartburn, acid regurgitation, pain on swallowing).

  • Long-term management and prevention of relapse in reflux oesophagitis.

  • Prevention of gastroduodenal ulcers induced by non-selective non-steroidal anti- inflammatory drugs (NSAIDs) in patients at risk with a need for continuous NSAID treatment.

Pantobex Delayed Release Tablet 40 mg

  • In combination with two appropriate antibiotics (see Dosage) for the eradication of H.pylori in patients with peptic ulcers with the objective of reducing the recurrence of duodenal and gastric ulcers caused by this microorganism.

  • Duodenal ulcer

  • Gastric ulcer

  • Moderate and severe reflux oesophagitis

Dosing

4.2. Posology and method of administration
Pantobex Delayed Release Tablet 20 mg
Pantobex 20 mg delayed-release tablets should not be chewed or crushed, and should be swallowed whole with water.

Pantobex Dosage Table 1



Pantobex Delayed Release Tablet 40 mg
Pantobex 40 mg delayed-release tablets should not be chewed or crushed, and should be swallowed whole with water.

Pantobex Dosage Table 2



Special Patient Populations
Pediatric patients:
The experience in children is limited. Pantoprazole 20 mg and 40 mg tablet is not recommended for use in children below 12 years of age due to limited data on safety and efficacy in this age group. Pantoprazole 40 mg powder for solution for injection is not recommended for use in patients below 18 years of age.
Impaired hepatic function:
A daily dose of Pantoprazole 20 mg should not be exceeded in patients with severe liver impairment (See section 4.4 – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information).
In addition, Pantoprazole 40 mg tablet must not be used in combination treatment (e.g. amoxicillin, clarithromycin,) for eradication of H. pylori in patients with moderate to severe hepatic dysfunction since currently no data are available on the efficacy and safety of pantoprazole in combination treatment of these patients (See section 4.3).
Impaired renal function:
No dose adjustment is necessary in those with impaired renal function.
In addition, pantoprazole 40 mg tablet must not be used in combination treatment (e.g. amoxicillin, clarithromycin) for eradication of H. pylori in patients with impaired renal function, since currently no data are available on the efficacy and safety of pantoprazole in combination treatment for these patients.
Elderly patients:
Generally, no dose adjustment is necessary in elderly patients. However, the daily dose of 40mg should not be exceeded in treatment of gastric or duodenal ulcer.

Contraindications

4.3 Contraindications
Pantobex should generally not be used in cases of known hypersensitivity to one of the other constituents of Pantobex 20 mg, Pantobex 40 mg tablet or of the combination partners.
Pantobex 40 mg tablet must not be used in combination treatment for eradication of H.pylori in patients with moderate to severe liver or kidney function disturbances since currently no clinical data are available on the efficacy and safety of Pantoprazole 40 mg in combination treatment of these patients.