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National Drug Formulary

LATACOM EYE DROPS [SIN16927P]

Active ingredients: LATANOPROST | TIMOLOL MALEATE EQV TIMOLOL

View product's general information
Last updated on 9 October 2026

Product Info

LATACOM EYE DROPS

[SIN16927P]

Product information

Active Ingredient and Strength

LATANOPROST - 0.05 MG/ML
TIMOLOL MALEATE EQV TIMOLOL - 5 MG/ML

Dosage Form

SOLUTION, STERILE

Manufacturer and Country

DUOPHARMA (M) SDN BHD - MALAYSIA

Registration Number

SIN16927P

Licence Holder

DUOPHARMA (SINGAPORE) PTE LTD

Forensic Classification

PRESCRIPTION ONLY MEDICINES

Anatomical Therapeutic Chemical (ATC) code

S01ED51

Prescription-only Medicines with Exemptions for Supply without Prescription

NA

Indication

INDICATIONS:
Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma and ocular hypertension who are insufficiently responsive to another topical IOP lowering agent.

Dosing

POSOLOGY AND METHOD OF ADMINISTRATION:
Use in adults (including the elderly):
One drop in the affected eye(s) once daily.
The use of Latacom may be considered in patients who require both timolol and latanoprost, but it is unknown whether patients who are adequately controlled with timolol given twice daily plus latanoprost given once daily will be as well controlled with Latacom given once daily. Latacom should be used for the reduction of intraocular pressure in patients with open angle glaucoma and ocular hypertension who are insufficiently responsive to another intraocular lowering pressure medication.
Latacom should not be used more than once daily because latanoprost is most effective when given once daily. If there is an insufficient response to Latacom, then consideration should be given to using the individual agents with timolol dosed twice daily.
If one dose is missed, treatment should continue with the next dose as planned. The dose should not exceed one drop in the affected eye(s) daily.
If more than one topical ophthalmic drug is being used, they should be administered at least five minutes apart.
Contact lenses should be removed before instillation of the eye drops and may be reinserted after fifteen minutes (see section Warnings & Precautions – please refer to the Product Insert/Patient Information Leaflet published on HSA for the full drug information).
When using nasolacrimal occlusion or closing the eyelids for 2 minutes, the systemic absorption is reduced. This may result in a decrease in systemic side effects and an increase in local activity.

Use in children:
Safety and effectiveness in children and adolescents have not been established.

Contraindications

CONTRAINDICATIONS:
Latanoprost-timolol maleate is contraindicated in patients with:

  • Reactive airway disease including bronchial asthma, a history of bronchial asthma, or severe chronic obstructive pulmonary disease.

  • Sinus bradycardia, sick sinus syndrome, sino-atrial block, second or third degree atrioventricular block not controlled with pace-maker, overt cardiac failure, or cardiogenic shock.

  • Known hypersensitivity to latanoprost, timolol maleate, or any other component of the product